One of the main research areas of the group is the development of point-of-care diagnostic tools focusing on nucleic acid amplification that provide robust results and versatile applications.
Specifically, we have developed isothermal self replication DNA strategies using destabilizing probes for the identification of specific targets. Such approach is being developed for the identification of mRNA sequences as well as single nucleotide polymorphisms. In a similar manner, our group has also developed DNA templated chemical ligation strategies to achieve enzyme-free self replication.